Looking for online definition of myoneural junction in the Medical Dictionary? myoneural junction Related to myoneural junction: neuromuscular junction. However, whether changes in the NMJ precede | Neuromuscular Junction, Nerve and Motor | ResearchGate, the professional network for g: adalah ‎| ‎Must include: ‎adalah. A neuromuscular junction (or myoneural junction) is a chemical synapse formed by the contact between a motor neuron and a muscle fiber. It is at the  ‎Structure and function · ‎Development · ‎Toxins that affect the · ‎Diseases.


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Think of the neurotransmitter-receptor relationship as a lock and a key, where only one key will fit that lock.

The synaptic cleft refers to the space between the two cells and is only about 20 nanometers wide. Physiology of a Synapse Now that we know what makes up a synapse, we're ready to describe the function of the neuromuscular junction. Neuromuscular junction adalah important to neuromuscular junction adalah the big picture in mind.

So, what is that big picture? Synaptic transmission carries the excitatory signal from the neuron to the muscle cell, much like a bridge could connect two land masses.

Myoneural junction | definition of myoneural junction by Medical dictionary

Let's start with the motor neuron. Calcium enters the excited neuron, and the calcium stimulates exocytosis of the neurotransmitter. Where does the neurotransmitter go but neuromuscular junction adalah the synaptic cleft. The neurotransmitter secreted by the somatic motor neurons is neuromuscular junction adalah.

So, the acetylcholine diffuses across the cleft and binds to acetylcholine receptors within the muscle cell membrane.


Like a key unlocking a door, acetylcholine opens ion channels, and sodium ions diffuse into the muscle cell. It's important to note that acetylcholine does not remain in the synaptic cleft forever, but rather an enzyme called acetylcholinesterase catalyzes the breakdown of acetylcholine, and where is it located - in neuromuscular junction adalah synaptic neuromuscular junction adalah.

This enzyme breaks down acetylcholine and therefore prevents overcontraction, or prevents contraction for lasting longer than necessary.

Since sodium is neuromuscular junction adalah positive ion, it depolarizes and thus excites the skeletal muscle cell membrane as it enters. Now, the excitatory impulse has transferred from the motor neuron to the muscle cell, much like a car would cross a bridge from one land mass to the next.

Neuromuscular Junction

The function of the NMJ is to transmit signals from the motor neuron to the skeletal muscle fibre quickly and reliably, to ensure precise control of skeletal muscle contraction and therefore voluntary movement. The reliability of transmission is aided by neuromuscular junction adalah architecture multiple active zones, junctional folds that promotes high levels of transmitter release, large and reliable postsynaptic responses to transmitter binding and rapid termination of signalling events.

In the last century, the structure and function neuromuscular junction adalah the NMJ has been extensively studied, which has been instrumental in uncovering many of the fundamental processes of chemical synaptic transmission.


The somatic neuromuscular junction is the site of communication between motor neurons and skeletal muscle fibres. Specialisations of the neuromuscular junction mean that activity in and release of transmitter from motor neurons produces contraction of skeletal muscle fibres rapidly and reliably.

The neuromuscular junction comprises four cell types: The motor nerve terminal contains synaptic vesicles, filled with neurotransmitter, which release their transmitter into the synaptic cleft at multiple neuromuscular junction adalah sites called active zones, in response to action potential firing.

Junctional folds are unique to the neuromuscular junction, increasing the reliability of transmission by localisation of acetylcholine neuromuscular junction adalah to the crests of the folds and enhancing the effect of depolarisation by localisation of sodium channels in the troughs. Schwann cells are essential for the development and maintenance of the neuromuscular junction neuromuscular junction adalah play important roles in the remodelling and regeneration of damaged neuromuscular junctions.


Acetylcholinesterase in the synaptic cleft hydrolyses acetylcholine and limits the temporal and spatial effects of released of acetylcholine, ensuring precision of muscle control.